Great you could get it to compile!! And yes indeed, qt5 also installed for me on that different folder you mention. I don't remember copying things to /usr/local/opt/qt5 (I don't have that folder in my computer), in my case brew updated the search paths so that "qmake" and other qt tools are available directly in the command line, and hence, the makefile finds them. But I did this many months ago, so maybe some of the brew scripts have changed 
In any case, glad you got it to work!
I am also using the intel version of openMSX now that you mention it. Maybe I'll try to see if I can produce an arm binary for that
@Sylvester: you are right! it's as easy as that! I just downloaded the 0.17 sources from the openMSX website, typed the command @Sylvester mentioned and a working arm binary was generated for openMSX! nice, now I have both emulator and debugger running natively
just run `make staticbindist`, it will download the dependencies automatically. I also have an openMSX ARM version running here
Oh ! Nice ! Thank you !
Done
Here openMSX 17 for Mac M1 (ARM) : http://ebsoft.fr/msx/openmsx-17.0-unknown-mac-aarch64-bin.dmg
I think it's even more interesting to have a binary of the latest debugger.... Right?
EDIT: ah, that is what you posted on the previous page Thanks! Can someone also build one for x86-64 and Windows, please?
just run `make staticbindist`, it will download the dependencies automatically. I also have an openMSX ARM version running here
Oh ! Nice ! Thank you !
Done
Here openMSX 17 for Mac M1 (ARM) : http://ebsoft.fr/msx/openmsx-17.0-unknown-mac-aarch64-bin.dmg
Wait, wasn't that version already available on our website? See
https://github.com/openMSX/openMSX/releases/download/RELEASE...